11/25/2022 0 Comments Justinmind save textfield![]() ![]() The output of the biosensor can be either a color change on the surface of the wearable device, or an electrical signal via exchange of electrons. The latter can send wireless signals to a mobile app to alert users of fentanyl consumption. The biosensor uses a two-plasmid design (see hyperlink the Biosensor), enclosed within a hydrogel (see hyperlink Electrochemistry), and is connected via electrodes to a small printed circuit board. To achieve our goal of decreasing accidental fentanyl overdoses, we have designed a wearable biosensor device for monitoring of small molecules in the wearer’s sweat and interstitial fluid. With recent advances and increased awareness in wearable biosensors, our team was inspired to design and create a wearable biosensor device integrating the latest research outcomes to tackle current world-wide issues. ![]() The design of our entire project was also inspired by recent work from the Wang and Mercier labs (University of California) who showed that monitoring of sweat and interstitial fluid in humans is possible with biosensors (Kim et al., 2018). 2015), and another of his published works have provided us with a sequence for an entirely synthetic, highly sensitive fentanyl receptor (Bick et al., 2017). His manuscripts have given us tremendous insight on constructing biosensors in yeast cells (Feng et al. David Baker, a biochemist currently working on protein engineering. In regards to the biological aspect of our project, we were inspired by the works of Dr. ![]() Currently, while some resources exist in specific locations to discourage accidental fentanyl ingestion and potential overdoses before drug consumption, few resources, if any, exist to alert a user to seek medical attention before it is too late. “Many times the consumption of fentanyl is involuntary” - Relais Methadone Addiction Center worker with 10 years of experience.īeing shown the Canadian federal statistics on drug overdoses and seeing that 93% of all opioid-related deaths were unintentional in 2019 encouraged us to decrease accidental overdoses. Electrochemistry (includes Hydrogels and Redox) Quantifen wearable biosensor prototype design V.2.0ģ. ![]()
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